P-gp inhibitor 1 ( —— )

产品货号. M26354 CAS No. 2050747-49-2

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产品名称

P-gp inhibitor 1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells).
产品描述

P-gp inhibitor 1 inhibits reversing P-glycoprotein-mediated multidrug resistance with an EC50 of 57.9 nM (K562/A02 cells).(In Vitro):In K562/A02 MDR cells, P-gp inhibitor 1 (0.1, 1, 5 μM, 1 h) boosts the potency of other MDR-related cytotoxic agents with different structures, increases the accumulation of DOX, blocks Pgp-mediated Rh123 efflux, and suppresses P-gp ATPase activity.
同义词

——
通路

Others
靶点

Other Targets
受体

Histamine Receptor
研究领域

——
适应症

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1.Miura M, Uno T. Clinical pharmacokinetics of fexofenadine enantiomers. Expert Opin Drug Metab Toxicol. 2010 Jan;6(1):69-74.

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